Nonspecific cross reacting antigen as a marker for human polymorphs, macrophages and monocytes
P Burtin, PC Quan, MC Sabine - Nature, 1975 - nature.com
P Burtin, PC Quan, MC Sabine
Nature, 1975•nature.comWE have described1 an antigen able to cross react with the carcinoembryonic antigen of the
digestive system (CEA) and named it nonspecific cross reacting antigen (NCA) because of
its reaction with CEA and its lack of tissue and cancer specificity. NCA was found in
perchloric extracts of gastrointestinal tumours and in lesser amounts in those of non-
cancerous mucosa, lung and spleen. The same antigen has been described under different
names (NGP, CCEA II) in other laboratories2, 3. We pointed out that NCA bore a specific …
digestive system (CEA) and named it nonspecific cross reacting antigen (NCA) because of
its reaction with CEA and its lack of tissue and cancer specificity. NCA was found in
perchloric extracts of gastrointestinal tumours and in lesser amounts in those of non-
cancerous mucosa, lung and spleen. The same antigen has been described under different
names (NGP, CCEA II) in other laboratories2, 3. We pointed out that NCA bore a specific …
Abstract
WE have described1 an antigen able to cross react with the carcinoembryonic antigen of the digestive system (CEA) and named it nonspecific cross reacting antigen (NCA) because of its reaction with CEA and its lack of tissue and cancer specificity. NCA was found in perchloric extracts of gastrointestinal tumours and in lesser amounts in those of non-cancerous mucosa, lung and spleen. The same antigen has been described under different names (NGP, CCEA II) in other laboratories2,3. We pointed out that NCA bore a specific antigenic determinant not shared by CEA1.
nature.com