K Cl co-transport: immunocytochemical and functional evidence for more than one KCC isoform in high K and low K sheep erythrocytes
PK Lauf, J Zhang, E Delpire, REW Fyffe… - … and Physiology Part A …, 2001 - Elsevier
K Cl co-transport (COT) is significantly higher in low K (LK), L-antigen (L) positive, than in
high K (HK), M-antigen (M) positive, sheep red blood cells (SRBCs) and is inhibited by
sheep allo-anti-Ll antibody. To answer the question of whether this difference in K Cl co-
transport activity resides at the level of the transporter or its regulation, a combined
immunocytochemical and functional approach was taken. At least four isoforms of K Cl
COT encoded by different KCC genes are known, with 12 transmembrane domains and …
high K (HK), M-antigen (M) positive, sheep red blood cells (SRBCs) and is inhibited by
sheep allo-anti-Ll antibody. To answer the question of whether this difference in K Cl co-
transport activity resides at the level of the transporter or its regulation, a combined
immunocytochemical and functional approach was taken. At least four isoforms of K Cl
COT encoded by different KCC genes are known, with 12 transmembrane domains and …
