Complete DiGeorge syndrome: development of rash, lymphadenopathy, and oligoclonal T cells in 5 cases
ML Markert, MJ Alexieff, J Li, M Sarzotti… - Journal of allergy and …, 2004 - Elsevier
BACKGROUND: Five patients with DiGeorge syndrome presented with infections, skin
rashes, and lymphadenopathy after the newborn period. T-cell counts and function varied
greatly in each patient. Initial laboratory testing did not suggest athymia in these patients.
OBJECTIVE: The purpose of this study was to determine whether the patients had significant
immunodeficiency. METHODS: Research testing of peripheral blood included immunoscope
evaluation of T-cell receptor β variable gene segment repertoire diversity, quantification of T …
rashes, and lymphadenopathy after the newborn period. T-cell counts and function varied
greatly in each patient. Initial laboratory testing did not suggest athymia in these patients.
OBJECTIVE: The purpose of this study was to determine whether the patients had significant
immunodeficiency. METHODS: Research testing of peripheral blood included immunoscope
evaluation of T-cell receptor β variable gene segment repertoire diversity, quantification of T …