Immunity to Listeria infection

BT Edelson, ER Unanue - Current opinion in immunology, 2000 - Elsevier
BT Edelson, ER Unanue
Current opinion in immunology, 2000Elsevier
Infection with Listeria monocytogenes is a well studied model for understanding host
resistance to intracellular bacteria. Recent advances in the study of Listeria have carefully
quantitated the response of CD8+ T cells to infection and analyzed the effector functions of
these cells in vivo. A surprising role for antibody in mediating resistance to Listeria has also
recently emerged, providing new insight into the mechanisms of host defense.
Infection with Listeria monocytogenes is a well studied model for understanding host resistance to intracellular bacteria. Recent advances in the study of Listeria have carefully quantitated the response of CD8+ T cells to infection and analyzed the effector functions of these cells in vivo. A surprising role for antibody in mediating resistance to Listeria has also recently emerged, providing new insight into the mechanisms of host defense.
Elsevier