[HTML][HTML] Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagon promoter-ghrelin transgenic mice
H Iwakura, K Hosoda, C Son, J Fujikura… - Journal of Biological …, 2005 - ASBMB
We developed and analyzed two types of transgenic mice: rat insulin II promoter-ghrelin
transgenic (RIP-G Tg) and rat glucagon promoter-ghrelin transgenic mice (RGP-G Tg). The
pancreatic tissue ghrelin concentration measured by C-terminal radioimmunoassay (RIA)
and plasma desacyl ghrelin concentration of RIP-G Tg were about 1000 and 3.4 times
higher than those of nontransgenic littermates, respectively. The pancreatic tissue n-
octanoylated ghrelin concentration measured by N-terminal RIA and plasma n-octanoylated …
transgenic (RIP-G Tg) and rat glucagon promoter-ghrelin transgenic mice (RGP-G Tg). The
pancreatic tissue ghrelin concentration measured by C-terminal radioimmunoassay (RIA)
and plasma desacyl ghrelin concentration of RIP-G Tg were about 1000 and 3.4 times
higher than those of nontransgenic littermates, respectively. The pancreatic tissue n-
octanoylated ghrelin concentration measured by N-terminal RIA and plasma n-octanoylated …
