The relation of islet amyloid to the clinical type of diabetes

AL Maloy, DS Longnecker, ER Greenberg - Human pathology, 1981 - Elsevier
Islets were evaluated for the presence of amyloid deposits in 169 pancreases removed at
autopsy. Islet amyloid occurred in 17 of 142 (12 per cent) of nondiabetics and in 16 of 27 (59
per cent) of diabetics. When diabetics were divided into categories according to clinical
severity of disease, the insulin treated diabetics had the highest prevalence (89 per cent),
the most diffuse distribution, and the most severe degree of islet amyloidosis. Amyloid was
not found in any pancreases from subjects under 40 years of age. Above the age of 40, there …