[HTML][HTML] Tuberous sclerosis complex diagnostic criteria update: recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference
H Northrup, DA Krueger, S Roberds, K Smith… - Pediatric …, 2013 - Elsevier
Background Tuberous sclerosis complex is highly variable in clinical presentation and
findings. Disease manifestations continue to develop over the lifetime of an affected
individual. Accurate diagnosis is fundamental to implementation of appropriate medical
surveillance and treatment. Although significant advances have been made in the past 15
years in the understanding and treatment of tuberous sclerosis complex, current clinical
diagnostic criteria have not been critically evaluated or updated since the last clinical …
findings. Disease manifestations continue to develop over the lifetime of an affected
individual. Accurate diagnosis is fundamental to implementation of appropriate medical
surveillance and treatment. Although significant advances have been made in the past 15
years in the understanding and treatment of tuberous sclerosis complex, current clinical
diagnostic criteria have not been critically evaluated or updated since the last clinical …