The binding of iron to transferrin and to other serum components at different degrees of saturation with iron.
C Heul, HG Van Eijk, B Leijnse - Clinica Chimica Acta, 1972 - cabdirect.org
C Heul, HG Van Eijk, B Leijnse
Clinica Chimica Acta, 1972•cabdirect.orgThe transferrin content of normal human serum is in general 20% lower than should be
expected from the total Fe-binding capacity. At saturation degrees higher than 50%, Fe is
distributed over serum proteins in addition to transferrin. The addition of HCO 3-or ascorbic
acid and differences in time or temperature have no influence on the binding of Fe to
transferrin at saturation degrees between 60 to 100%. The immunochemical estimation of
transferrin which is simple, reliable and specific is preferred.
expected from the total Fe-binding capacity. At saturation degrees higher than 50%, Fe is
distributed over serum proteins in addition to transferrin. The addition of HCO 3-or ascorbic
acid and differences in time or temperature have no influence on the binding of Fe to
transferrin at saturation degrees between 60 to 100%. The immunochemical estimation of
transferrin which is simple, reliable and specific is preferred.
Abstract
The transferrin content of normal human serum is in general 20% lower than should be expected from the total Fe-binding capacity. At saturation degrees higher than 50%, Fe is distributed over serum proteins in addition to transferrin. The addition of HCO 3-or ascorbic acid and differences in time or temperature have no influence on the binding of Fe to transferrin at saturation degrees between 60 to 100%. The immunochemical estimation of transferrin which is simple, reliable and specific is preferred.
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