Rifampin is a potent inducer of hepatic P450 oxidative enzymes. Clinically important drug
interactions have been documented between rifampin and numerous other drugs, such as
oral anticoagulants, oral contraceptives, cyclosporine, digitalis, and ketoconazole. New,
potentially clinically significant rifampin drug interactions have been reported for haloperidol,
several antiarrhythmics, fluconazole, diltiazem, and select benzodiazepines. Further
research has been conducted for previously reported drug interactions with rifampin …