Molecular imaging of bacterial infections: overcoming the barriers to clinical translation

AA Ordonez, MA Sellmyer, G Gowrishankar… - Science translational …, 2019 - science.org
AA Ordonez, MA Sellmyer, G Gowrishankar, CA Ruiz-Bedoya, EW Tucker, CJ Palestro…
Science translational medicine, 2019science.org
Clinical diagnostic tools requiring direct sample testing cannot be applied to infections deep
within the body, and clinically available imaging tools lack specificity. New approaches are
needed for early diagnosis and monitoring of bacterial infections and rapid detection of drug-
resistant organisms. Molecular imaging allows for longitudinal, noninvasive assessments
and can provide key information about infectious processes deep within the body.
Clinical diagnostic tools requiring direct sample testing cannot be applied to infections deep within the body, and clinically available imaging tools lack specificity. New approaches are needed for early diagnosis and monitoring of bacterial infections and rapid detection of drug-resistant organisms. Molecular imaging allows for longitudinal, noninvasive assessments and can provide key information about infectious processes deep within the body.
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