DQ-Red BSA trafficking assay in cultured cells to assess cargo delivery to lysosomes
Lysosomes are the terminal end of the endocytic pathway having acidic environment
required for active hydrolases that degrade the cargo delivered to these compartments. This
process of cargo delivery and degradation by endo-lysosomes is a tightly regulated process
and important for maintaining cellular homeostasis. Cargos like EGF (Epidermal Growth
Factor), Dil-LDL (3, 3'-Dioctadecylindocarbocyanine-Low Density Lipoprotein), Dextran, DQ-
BSA (Dye Quenched-Bovine Serum Albumin) etc., are routinely used by researchers to …
required for active hydrolases that degrade the cargo delivered to these compartments. This
process of cargo delivery and degradation by endo-lysosomes is a tightly regulated process
and important for maintaining cellular homeostasis. Cargos like EGF (Epidermal Growth
Factor), Dil-LDL (3, 3'-Dioctadecylindocarbocyanine-Low Density Lipoprotein), Dextran, DQ-
BSA (Dye Quenched-Bovine Serum Albumin) etc., are routinely used by researchers to …
