Determination of the minimal clinically important difference scores for the Cystic Fibrosis Questionnaire-Revised respiratory symptom scale in two populations of …
AL Quittner, AC Modi, C Wainwright, K Otto, J Kirihara… - Chest, 2009 - Elsevier
Background The Cystic Fibrosis Questionnaire-Revised is a validated patient-reported
outcome containing both generic scales and scales specific to cystic fibrosis. The minimal
clinically important difference score for a PRO corresponds to the smallest clinically relevant
change a patient can detect. MCID scores for the CFQ-R respiratory symptom (CFQ-R-
Respiratory) scale were determined using data from two 28 day, open-label, tobramycin
inhalation solution (TIS) studies in patients with CF and chronic Pseudomonas aeruginosa …
outcome containing both generic scales and scales specific to cystic fibrosis. The minimal
clinically important difference score for a PRO corresponds to the smallest clinically relevant
change a patient can detect. MCID scores for the CFQ-R respiratory symptom (CFQ-R-
Respiratory) scale were determined using data from two 28 day, open-label, tobramycin
inhalation solution (TIS) studies in patients with CF and chronic Pseudomonas aeruginosa …